The Relationship between β-blockers and Mental Health

Beta-blockers (β-blockers) are pharmacotherapeutics that have been used to treat patients with cardiovascular symptoms since their discovery in the 1960s. They work by targeting B1 and B2 receptors which involved stress response, consequently lead reduced activation of “flight-or-fight mechanism”. It has also noticed β-blockers can be beneficial treating anxiety disorders other mental health complications. Currently, only approved drugs for conditions include benzodiazepines selective serotonin reuptake inhibitors. Historically, there strong resistance use treatment because prevalence depressive during treatment. Recently, a growing number studies seen is no relationship between depression patients. Although still adverse effects related usage β-blockers, investigating may suggest potential therapeutic option treatments. This review explores history mechanism action, developments as current health.